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WP1: Integration of Epo-induced Signal Transduction
About this Project:
Items related to WP1: Integration of Epo-induced Signal Transduction.

People (8)
Disciplines: Modeller, Experimentalist
Roles: Not specified
Expertise: Biochemistry, Molecular Biology, Mathematical Modelling
Projects: WP1: Integration of Epo-induced Signal Transduction, WP3: Cell Fate Decisions of Erythroid Progenitor Cells, WP5: Translational Application for the Characterization and ex vivo Expansion of Human Erythroid Progenitor Cells
Institutions: DKFZ
Tools: Java, Matlab, Model Integration, ODE, R, Cell and tissue culture, Cell biology, Cell designer, Cytometry and fluorescent microscopy, Immunological techniques
Disciplines: Not specified
Roles: Not specified
Expertise: Not specified
Projects: WP1: Integration of Epo-induced Signal Transduction, WP2: Link of Signal Transduction to Gene Regulatory Network, WP3: Cell Fate Decisions of Erythroid Progenitor Cells, WP4: Cross-talk with Modulators - Epo with TGFß and Novel Factors, WP5: Translational Application for the Characterization and ex vivo Expansion of Human Erythroid Progenitor Cells
Institutions: DKFZ
Tools: Not specified
Disciplines: Not specified
Roles: Not specified
Expertise: Not specified
Projects: WP1: Integration of Epo-induced Signal Transduction, WP3: Cell Fate Decisions of Erythroid Progenitor Cells, WP4: Cross-talk with Modulators - Epo with TGFß and Novel Factors
Institutions: DKFZ
Tools: Not specified
Disciplines: Not specified
Roles: Not specified
Expertise: Not specified
Projects: WP1: Integration of Epo-induced Signal Transduction, WP3: Cell Fate Decisions of Erythroid Progenitor Cells
Institutions: DKFZ
Tools: Not specified
Projects: WP1: Integration of Epo-induced Signal Transduction, WP3: Cell Fate Decisions of Erythroid Progenitor Cells
Institutions: University of Freiburg
Tools: Identifiability Analysis, Mathematical Modelling, Matlab, ODE, Parameter Estimation, Web services, Cytometry and fluorescent microscopy
Institutions (3)
Investigations (0+1)
Studies (0+3)
Assays (0+3)
Data files (0+2)
Models (0+4)
Publications (6)
Protein abundance of AKT and ERK pathway components governs cell type‐specific regulation of proliferation
Authors: Lorenz Adlung, Sandip Kar, Marie-Christine Wagner, Bin She, Sajib Chakraborty, Jie Bao, Susen Lattermann, Melanie Boerries, Hauke Busch, Patrick Wuchter, Anthony D Ho, Jens Timmer, Marcel Schilling, Thomas Höfer, Ursula Klingmüller
Date Published: 24th Jan 2017
Projects: WP1: Integration of Epo-induced Signal Transduction, WP2: Link of Signal Transduction to Gene Regulatory Network, WP3: Cell Fate Decisions of Erythroid Progenitor Cells, WP5: Translational Application for the Characterization and ex vivo Expa...
Journal: Mol Syst Biol
Abstract (Expand)
Created: 31st Jan 2017 at 13:58  Last updated: 31st Jan 2017 at 14:00
Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells
Authors: Ruth Merkle, Bernhard Steiert, Florian Salopiata, Sofia Depner, Andreas Raue, Nao Iwamoto, Max Schelker, Helge Hass, Marvin Wäsch, Martin E. Böhm, Oliver Mücke, Daniel B. Lipka, Christoph Plass, Wolf D. Lehmann, Clemens Kreutz, Jens Timmer, Marcel Schilling, Ursula Klingmüller
DOI: 10.1371/journal.pcbi.1005049
Date Published: 5th Aug 2016
Projects: WP1: Integration of Epo-induced Signal Transduction, WP3: Cell Fate Decisions of Erythroid Progenitor Cells
Journal: PLoS Comput Biol
Abstract (Expand)
Created: 13th Dec 2016 at 11:28  Last updated: 13th Dec 2016 at 11:29
Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation
Authors: N. Iwamoto, L. A. D'Alessandro, S. Depner, B. Hahn, B. A. Kramer, P. Lucarelli, A. Vlasov, M. Stepath, M. E. Bohm, D. Deharde, G. Damm, D. Seehofer, W. D. Lehmann, U. Klingmuller, Marcel Schilling
PubMed ID: 26838549
Date Published: 4th Feb 2016
Projects: WP1: Integration of Epo-induced Signal Transduction
Journal: Sci Signal
Abstract (Expand)
Created: 28th Apr 2016 at 13:22
Authors: L. A. D'Alessandro, R. Samaga, T. Maiwald, S. H. Rho, S. Bonefas, A. Raue, N. Iwamoto, A. Kienast, K. Waldow, R. Meyer, Marcel Schilling, J. Timmer, S. Klamt, U. Klingmuller
PubMed ID: 25905717
Date Published: 23rd Apr 2015
Projects: WP1: Integration of Epo-induced Signal Transduction
Journal: PLoS Comput Biol
Abstract (Expand)
Created: 28th Apr 2016 at 13:19
Authors: A. Raue, Bernhard Steiert, M. Schelker, C. Kreutz, T. Maiwald, H. Hass, J. Vanlier, Christian Tönsing, Lorenz Adlung, R. Engesser, W. Mader, T. Heinemann, J. Hasenauer, Marcel Schilling, T. Hofer, E. Klipp, F. Theis, U. Klingmuller, B. Schoberl, J. Timmer
PubMed ID: 26142188
Date Published: 3rd Jul 2015
Projects: WP1: Integration of Epo-induced Signal Transduction
Journal: Bioinformatics
Abstract (Expand)
Created: 13th Aug 2015 at 07:12